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Sakiko Hirose Selected Research

Tolerogen

8/2010Rice seed ER-derived protein body as an efficient delivery vehicle for oral tolerogenic peptides.
4/2009Deposition of a recombinant peptide in ER-derived protein bodies by retention with cysteine-rich prolamins in transgenic rice seed.
11/2007Development of transgenic rice seed accumulating a major Japanese cedar pollen allergen (Cry j 1) structurally disrupted for oral immunotherapy.

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Sakiko Hirose Research Topics

Disease

5Seasonal Allergic Rhinitis (Hay Fever)
01/2013 - 12/2006
3Hypersensitivity (Allergy)
12/2012 - 01/2008
1Pain (Aches)
01/2018
1Hemorrhage
01/2018
1Autoimmune Diseases (Autoimmune Disease)
12/2012
1Asthma (Bronchial Asthma)
12/2011
1Body Weight (Weight, Body)
04/2011
1Hypercholesterolemia
04/2011
1Neurodegenerative Diseases (Neurodegenerative Disease)
08/2010
1Alzheimer Disease (Alzheimer's Disease)
08/2010
1Amyloid Plaque
08/2010
1Dust Mite Allergy
01/2008

Drug/Important Bio-Agent (IBA)

5AllergensIBA
01/2013 - 11/2007
3VaccinesIBA
05/2012 - 01/2008
3Proteins (Proteins, Gene)FDA Link
12/2011 - 11/2007
3T-Lymphocyte Epitopes (Epitopes, T Lymphocyte)IBA
12/2011 - 04/2009
3Peptides (Polypeptides)IBA
08/2010 - 11/2007
3TolerogenIBA
08/2010 - 11/2007
2Pharmaceutical PreparationsIBA
01/2018 - 04/2011
2Dermatophagoides pteronyssinus antigen p 1IBA
12/2011 - 01/2008
1Ketoprofen (Orudis)FDA LinkGeneric
01/2018
1AntigensIBA
01/2013
1Interleukin-10 (Interleukin 10)IBA
12/2012
1Dermatophagoides farinae antigen f 2IBA
05/2012
1Subunit VaccinesIBA
12/2011
1gamma-sitosterol (beta-sitosterol)IBA
04/2011
1lactostatinIBA
04/2011
1Glutens (Glutelin)IBA
04/2011
1Lactoglobulins (beta-Lactoglobulin)FDA Link
04/2011
1HDL LipoproteinsIBA
04/2011
1HDL CholesterolIBA
04/2011
1LDL Lipoproteins (beta Lipoproteins)IBA
04/2011
1LDL CholesterolIBA
04/2011
1Amyloid beta-PeptidesIBA
08/2010
1Immunoglobulin E (IgE)IBA
11/2007
1Cysteine (L-Cysteine)FDA Link
11/2007
1ProlaminsIBA
11/2007
1Protein Subunit VaccinesIBA
12/2006

Therapy/Procedure

5Immunotherapy
01/2013 - 12/2006
2Oral Administration
01/2013 - 04/2011